The blue peak depicts CellPrint™ signal well-separated from the background peak in gray.
Regular Flow Cytometry
Here, the blue peak represents assessment of the same molecule as above. However, with standard methods the peak was difficult to discriminate from background.
Flow cytometry is a powerful analytical modality principally because it can be used to assign molecular expression to specific cellular subpopulations. Its weak detection sensitivity however limits its utility.
CellPrint™ transforms regular flow cytometry with a proprietary signal amplification method that greatly enhances sensitivity, while conserving regular flow cytometry’s strengths.
This enhanced sensitivity allows for precise, accurate, and reproducible quantitative analysis of molecular expression in specific cell lineages in peripheral blood. CellPrint™ often resolves molecules that are undetectable by standard methods.
CellPrint scientists employ this sensitivity to reveal otherwise unknown relationships between lineage-specific molecular expression and the clinical status of patients. These relationships provide new insights about pathophysiology and help identify novel biomarkers and drug targets.
CellPrint™ has been extensively validated (peer reviewed and published) and applied to the analysis of surface and intracellular molecules.